In a large mixing bowl, whisk together the bourbon, water, brown sugar, minced garlic, Dijon mustard, salt, and black pepper.
Scrape the seeds from the split vanilla bean and add them to the mixture, then add the vanilla bean itself.
Place the pork chops in a large ziplock bag and pour the bourbon and vanilla marinade over them.
Seal the bag and massage the marinade into the pork chops, making sure they are evenly coated.
Refrigerate for at least 3 hours, or overnight for maximum flavor.
When ready to cook, preheat your grill or skillet to medium-high heat.
Remove the pork chops from the marinade and discard the excess marinade.
Grill or pan-sear the pork chops for approximately 6-7 minutes per side, or until the internal temperature reaches 145°F for medium, or 160°F for well done.
Let the pork chops rest for 5 minutes before serving to allow the juices to redistribute.
Serve and enjoy your delicious bourbon and vanilla-brined pork chops!